منابع مشابه
Sex pili mutants isolated by macarbomycin treatment.
Macarbomycin (MM) preferentially kills Escherichia coli carrying episomes derepressed for sex pili formation (drd episomes). Using MM, we have isolated various types of mutants from both F-lac.tet and R100-1 episomes and have classified them into two types by sex pili formation. Among 26 mutants, 20 could not produce pili and had lost both the ability for conjugal transmission and sensitivity t...
متن کاملStudies on sex pili: mutants of the sex factor F in Escherichia coli defective in bacteriophage-adsorbing function of F pili.
Ultraviolet irradiation or nitrosoguanidine treatment of Escherichia coli K-12 strain JE3100 (F'(8)/fla pil) led to the isolation of six mutants defective in F pili function. The defects were shown to be caused by mutations in the F factor. The mutants retained conjugal fertility, although they were less efficient than parental F'(8) strain, and continued to synthesize F pili. Three of the muta...
متن کاملConjugate-like immunogens produced as protein capsular matrix vaccines.
Capsular polysaccharides are the primary antigenic components involved in protective immunity against encapsulated bacterial pathogens. Although immunization of adolescents and adults with polysaccharide antigens has reduced pathogen disease burden, pure polysaccharide vaccines have proved ineffective at conferring protective immunity to infants and the elderly, age cohorts that are deficient i...
متن کاملEnvelope Glycoprotein Trimers as HIV-1 Vaccine Immunogens
The HIV-1 envelope glycoprotein spike is the target of neutralizing antibody attack, and hence represents the only relevant viral antigen for antibody-based vaccine design. Various approaches have been attempted to recapitulate Env in membrane-anchored and soluble forms, and these will be discussed here in the context of recent successes and challenges still to be overcome.
متن کاملEvaluation of filamentous bacteriophage as immunogens in Atlantic salmon.
farming industry for several years. The life cycle of salmon dictates that they are reared in fresh water for the initial part of their life with maturation in salt water before harvest. It is while maturing in sea cages that salmon are susceptible to attack by marine parasites. Farmed salmon are present in much higher densities compared to wild populations and the close proximity of fish leads...
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ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1975
ISSN: 0022-1287
DOI: 10.1099/00221287-89-1-133